
Staying physically fit can help ward off heart trouble, even if your genetics put you at higher risk for clogged arteries, a new, large study suggests. The researchers looked at nearly 500,000 middle-aged and older adults and found those with higher fitness levels were less likely to develop heart disease over six years. And that was true even for people who carried gene variants that raise the odds of heart problems. That does not mean exercise erases the effects of genes, the researchers added. But if you do have a genetic vulnerability to heart disease, you’re better off being physically fit. “It’s likely that if you try to improve your fitness level through exercise, you’ll benefit,” said senior researcher Dr. Erik Ingelsson, a professor of medicine at Stanford University in California. How much, or what type, of exercise is “enough”? The study cannot answer those questions, Ingelsson said. His team did not test any particular exercise regimens. The researchers looked at how people’s fitness levels — gauged during a stationary bike workout — correlated with their risk of developing heart disease over the next six years. They found that regardless of the genes people carried, higher fitness levels meant a lower risk of heart trouble. Among the one-third of people at highest genetic risk, those with the highest fitness levels were 49 percent less likely… read on >