People living with an autoimmune disease are nearly twice as likely to suffer from mood problems like depression, anxiety or bipolar disorder, a new large-scale study says. The risk of mood disorders is 87% to 97% higher in people suffering from rheumatoid arthritis, inflammatory bowel disease, lupus, multiple sclerosis, psoriasis and Graves’ syndrome, researchers reported June 24 in the BMJ Mental Health. This risk remains higher even after accounting for other factors like age, income and family history of psychiatric disorders, researchers found. “Together, these results support the hypothesis that exposure to chronic inflammation may be associated with a greater risk for affective disorders,” concluded the research team led by Arish Mudra Rakshasa-Loots with the University of Edinburgh Center for Clinical Brain Sciences in the U.K. For the study, researchers drew on data from 1.5 million people participating in a new large-scale U.K. health study. Upon recruitment to the ongoing study, people provided a history of their physical and mental health. In all, more than 37,800 of the study participants reported living with an autoimmune condition. About 29% of people with an autoimmune illness said they’d been previously diagnosed with a mood disorder, compared with 18% of the general population, results show. This included more than 25% versus 15% diagnosed with depression, and 21% versus nearly 13% diagnosed with anxiety. Women with autoimmune diseases were… read on > read on >







