All Sauce from Weekly Gravy:

Preliminary data from the largest survey examining the quality of life for transgender and nonbinary Americans show they suffer high levels of unemployment and harassment. In the early findings, released Wednesday, the National Center for Transgender Equality gathered responses on 600 questions from more than 92,000 transgender and nonbinary Americans, age 16 and up, from every state in the country. This latest survey, conducted in late 2022, drew more than three times as many respondents as there were in 2015, the last time the survey was conducted. “You don’t see data sets like this,” survey leader Sandy James said during a media briefing, the New York Times reported. “Tens of thousands of trans people knew that it was imperative that they make their voices heard.” What did they want Americans to hear? Many respondents reported daunting financial challenges. Eighteen percent said they were unemployed, much higher than the national rate, and one-third said they had experienced homelessness at some point in their lives. More than one-quarter reported not seeing a doctor when they needed to in the previous year because of cost. But financial problems were not their only burden to bear: Nearly a third said they had been verbally harassed in the previous year, while 3% said they were physically attacked in the last year because of their gender identity. Still, they also shared positive…  read on >  read on >

Could drugs that give a boost to men’s sexual performance help them stave off Alzheimer’s disease? That’s the main finding from a study suggesting that erectile dysfunction meds like Cialis, Levitra and Viagra might lower the odds for the memory-robbing illness. The study wasn’t designed to prove cause-and-effect, cautioned British researchers at University College London. “More research is needed to confirm these findings, learn more about the potential benefits and mechanisms of these drugs and look into the optimal dosage,” explained study co-author Ruth Brauer, a lecturer in pharmacoepidemiology and medication safety at the university. She also believes that, “a randomized, controlled trial with both male and female participants is warranted to determine whether these findings would apply to women as well.” The findings were published Feb. 7 in the journal Neurology. Erectile dysfunction medications work by dilating blood vessels and increasing blood flow. The new study involved almost 270,000 men, averaging 59 years of age, who had all been newly diagnosed with erectile dysfunction (ED). A little more than half of them were prescribed an ED drug. None of the men had any cognitive or memory issues when they entered the study. Over five years of follow-up, 1,119 of the men were diagnosed with Alzheimer’s disease. Bauer’s team reported that men who were taking an ED drug had an 18% lower odds of developing…  read on >  read on >

Reducing homelessness by 25% could save nearly 2,000 lives lost each year to opioid overdoses, a new study estimates. It also could save 850 lives from alcohol poisoning and 540 from cocaine overdoses, researchers from the University of Georgia estimate. This is the first study to suggest that homelessness contributes to deaths from substance use, the researchers said. “One of the frustrations for people who study and recommend policy changes is that homelessness and the opioid crisis are persistent,” said researcher David Bradford, a professor with the University of Georgia’s School of Public and International Affairs. “Our study shows that there is a causal effect. Homelessness is making the opioid crisis worse.” For the study, researchers analyzed federal data kept on homeless people between 2007 and 2017, comparing it with death certificates with drug overdose or alcohol poisoning as the cause of death. Researchers found that even a small decrease in homelessness could save lives. For example, even a 10% decrease in homelessness could save more than 650 from death by opioid overdose, their results show. “That’s a lot of lives,” said researcher Felipe Lozano-Rojas, an assistant professor in the University of Georgia’s School of Public and International Affairs. “Deaths from opioids used to be a rare event, but it has become increasingly prevalent.” Evictions have skyrocketed in recent years, with the lifting of the…  read on >  read on >

No one’s brain is as sharp at 60 as it was at 20. However, new research supports the notion that folk’s brains can make subtle adjustments with age to compensate for that decline. A team of British researchers has found more evidence that as the mind ages, it sometimes recruits help from certain brain regions to make up for deficits elsewhere. This does not happen for everyone equally, stressed study lead author Dr. Ethan Knights. Still, “now that we’ve seen this compensation happening, we can start to ask questions about why it happens for some older people, but not others, and in some tasks, but not others,” said Knights, who works in the Medical Research Council Cognition and Brain Sciences Unit at Cambridge University. “Is there something special about these people — their education or lifestyle, for example — and if so, is there a way we can intervene to help others see similar benefits?,” Knights said in a university news release. His team published its findings Feb. 6 in the journal eLife. Working with researchers at the University of Sussex, Knights’ group sought to elucidate the brain’s means of coping with age. “Our ability to solve abstract problems is a sign of so-called ‘fluid intelligence,’ but as we get older, this ability begins to show significant decline,” noted senior study author Dr. Kamen Tsvetanov.…  read on >  read on >

Ohio resident Erica Hutson was in her 20s when she found out she had high cholesterol through a health check required by insurance. Because she was young and fit, Hutson shrugged off the test result. But Hutson changed her mind about it a decade later, when her father died of coronary artery disease in his 60s and she discovered it ran in her family. “His death really made me think about things and put my life into a whole different perspective,” said Hutson, now 37. More Americans need to follow Hutson’s example and discover their heart risk factors earlier in life, according to a new national survey conducted by Ohio State University’s Wexner Medical Center. Fewer than half of Americans know their blood pressure or ideal weight, and less than one in five know their cholesterol or blood sugar levels, the survey found. “Recognizing heart disease risk factors early and adequately treating them can potentially prevent heart attacks, strokes and heart failure. As a society, we need to shift from sick care to preventative care so people can live their best and fullest lives possible,” said Dr. Laxmi Mehta, director of preventative cardiology and women’s cardiovascular health at Wexner. The survey asked more than 1,000 adults nationwide if they knew their blood pressure level, ideal weight, cholesterol and blood sugar levels. The highest number knew…  read on >  read on >

A company in Ecuador that processed the cinnamon used in flavored applesauce pouches destined for the American market is the likely source of lead contamination in those products, U.S. investigators said. In an update to its investigation into recalled WanaBana, Weis and Schnucks brand cinnamon-flavored applesauce pouches, the U.S. Food and Drug Administration said a now-defunct Ecuadorian company called Carlos Aguilera is to blame for high amounts of lead in the product. Carlos Aguilera processed raw cinnamon sticks originating in Sri Lanka, the FDA explained. However, Ecuadorian officials analyzed the unprocessed cinnamon sticks, which were “found to have no lead contamination” before being processed. Lead contamination appears to have been introduced during processing at Carlos Aguilera, according to the FDA. Carlos Aguilera then sent the cinnamon to another company, Negasmart, which in turn sold it to Austrofoods, the manufacturer of the recalled applesauce pouches. The investigation reveals the complex international web of food suppliers, processors and manufacturers which makes FDA oversight of imported products sold in American supermarkets very tough, the agency said. Legally, the FDA’s hands are tied. “The FDA has limited authority over foreign ingredient suppliers who do not directly ship product to the U.S.,” the agency explained in its statement. “This is because their food undergoes further manufacturing/processing prior to export. Thus, the FDA cannot take direct action with Negasmart or Carlos Aguilera.”…  read on >  read on >

Divorce later in life might be harder on women than on men, based on patterns of antidepressant use in a new study of people aged 50 or older. Both sexes tended to increase their antidepressant use when going through a divorce, break-up or the death of a partner, researchers found. But women’s use of these drugs was greater than men’s, results show. Antidepressant use increased by 7% in women prior to a divorce and 6% before a break-up, compared to 5% and 3% for men, researchers found. Within a year, antidepressant use went back to normal levels for men. It was a different story for women, however. Women’s use tailed off only slightly immediately after the end of a relationship, and then increased again a year after and onward, results show. “The greater increases in [antidepressant] use associated with union dissolution among women in our study may indeed relate to the fact that the costs of union dissolution on mental health fall more heavily on women than men,” wrote researchers led by Yaoyue Hu, an associate professor with the Chongqing Medical University School of Public Health in Chongqing, China. This could have widespread repercussions around the world, researchers noted. “Gray divorce” from the age 50 onward is becoming more frequent in high-income countries, researchers said. Later-life depression is also relatively common, affecting an estimated 10%…  read on >  read on >

Music may be good medicine for older adults, boosting both their mental and physical health, a new survey finds. Virtually all people between the ages of 50 and 80 (98%) say they benefit in at least one health-related way from engaging with music, according to results from the latest University of Michigan National Poll on Healthy Aging. Three-quarters said music helps them relieve stress or relax, 65% said it helps their mental health and mood, and about 60% said they get energized or motivated by music. Overall, nine of 10 survey participants (89%) said music is very or somewhat important to them. “Music has the power to bring joy and meaning to life. It is woven into the very fabric of existence for all of humankind,” said Dr. Joel Howell, a professor of internal medicine at the University of Michigan Medical School who worked on the poll.  Music can benefit a variety of ailments related to aging, Howell added. “We know that music is associated with positive effects on measures from blood pressure to depression,” Howell said in a university news release. Most of the older adults surveyed said they listen to music, with 85% listening a few times a week and 80% watching musical performances a few times over the past year. Two in five (41%) attended a live concert. Fewer actually make music…  read on >  read on >

Depression and a rise in body temperature appear linked, although researchers say it’s not yet clear which causes which. Still, the findings offer a hint that manipulating body temperature might be a new form of therapy against depression. “To our knowledge, this is the largest study to date to examine the association between body temperature — assessed using both self-report methods and wearable sensors — and depressive symptoms in a geographically broad sample,” said study lead Ashley Mason, an associate professor of psychiatry at the University of California, San Francisco (UCSF). “Given the climbing rates of depression in the United States, we’re excited by the possibilities of a new avenue for treatment,” she added in a UCSF news release. The new study involved more than 20,000 people from 106 countries who wore a device that measured their body temperature. The study ran for seven months, beginning in early 2020. As a person’s level of depression severity rose, so, too, did their body temperatures, Mason’s group reported. The findings were published Feb. 5 in the journal Scientific Reports. There was also a trend suggesting that folks whose body temperatures remained stable over a 24-hour period also had higher risks for depression — but the finding didn’t quite meet statistical significance, the investigators said. It’s also unclear whether higher body temperature can help trigger depression, whether depression…  read on >  read on >

The Pearl Jam song “Jeremy” tells the story of a boy driven mad by bullies who commits suicide in front of his classroom. The song might reflect a real and ongoing threat to teens’ mental health, new research suggests. Teens being bullied face a greater risk of early-stage psychotic symptoms such as hallucinations or paranoia, according to findings published recently in the journal Nature. Bullied teenagers also have lower levels of a key neurotransmitter found in a part of the brain involved in regulating emotions, researchers said. The findings highlight the value of efforts to reduce bullying at schools, said lead researcher Naohiro Okada, a project associate professor with the University of Tokyo’s International Research Center for Neurointelligence. “Anti-bullying programs in schools that focus on promoting positive social interactions and reducing aggressive behaviors are essential for their own sake and to reduce the risk of psychosis and its subclinical precursors,” Okada said in a university news release. “These programs can help create a safe and supportive environment for all students, reducing the likelihood of bullying and its negative consequences,” Okada added. Researchers tracked bullying via questionnaires completed by Japanese teenagers, as well as the effect bullying had on their mental health. They found bullying associated with subclinical psychotic experiences in early adolescence — symptoms that come close to psychosis but do not meet the full…  read on >  read on >